Geneticin™ Selective Antibiotic (G418 Sulfate), Powder (Gibco™)

Geneticin™ Selection Antibiotic (G418 Sulfate) is produced by the bacterium Micromonospora rhodorangea and acts by binding the ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells. Resistance to Geneticin™ Selection Antibiotic (G418 Sulfate) is conferred by the E. coli APH(3’)–I and APH(3’)–II resistance genes.

Gibco™ Geneticin™ Selection Antibiotic (G418 Sulfate) is used as a selection antibiotic in the concentration range of 100–200 μg/mL for bacteria, or 200–500 μg/mL for most mammalian cells. This product is supplied as a powder and should be made into a stock solution of 10–50 mg/mL in water.

Other Choices and More Information
We offer a wide range of antibiotics and antimycotics in both powder and liquid formats.

See the complete list, or find products for:
• Contamination control
• Eukaryotic and bacterial selection

See recommendations for working concentrations for selection antibiotics.

Learn more about the use of antibiotics and antimycotics in cell culture, and review guidelines for decontaminating cultures.

Dual-Site cGMP Manufacturing and Quality Standard
Gibco™ Geneticin™ Selection Antibiotic (G418 Sulfate) is manufactured at a cGMP compliant facility, located in Paisley, Scotland, UK. The facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard. For supply chain continuity, we offer powdered Gibco™ Geneticin™ Selection Antibiotic (G418 Sulfate) products made in our New York facility (Cat. Nos. 11811098, 11811031, and 11811023). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard.