POROS™ XQ RoboColumn (Thermo Scientific™)

RoboColumn™ chromatography products are small columns provided in 8-column strips. They are useful for fully automated and parallel chromatographic separations using robotic liquid handling platforms. These particular RoboColumns contain POROS™ XQ resin, a 50-micron strong anion-exchange resin suitable for low-pressure applications, including large-scale downstream bioprocessing.

POROS XQ is a high-capacity, high-resolution, salt-tolerant resin that that enables >140 mg/mL dynamic binding capacity in the presence of up to 6.6 mS/cm NaCl, while delivering exceptional separation performance. A major improvement to the performance of traditional anion exchangers, POROS XQ resin sets the standard for strong anion exchange chromatography in both bind & elute or flow-through modes of operation.

Features of the resin:
• High dynamic binding capacity leading to reduced column size, smaller footprint, decreased water and buffer usage, and reduced cycling
• High resolution supporting improved product yield and purity, ultimately improving the cost of goods for the molecule being produced
• Robust salt tolerance allowing enhanced process design flexibility and streamlining of process flow
• Low operating back pressure and linear pressure versus flow responses driving flexible scalability
• Rigid polymeric bead with covalent surface chemistry for easier handling and packing, and superior physical and chemical stability enabling a more robust downstream purification process

RoboColumn is a registered trademark of ATOLL GmbH.