SMART Digest™ Trypsin Kits (Thermo Scientific™)

Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.

Key Features

Trypsin Protein Digestion

SMART Digest kits enable you to characterize and quantitate proteins faster, easier, and quicker than ever before. This version of the kit uses trypsin, which cleaves peptides on the C-terminal side of lysine and arginine amino acid residues.

Easy and simple
  • Significantly increased speed of sample processing
  • Simple process
  • Easily automate entire protocol for high-throughput processing
Reliable Results
  • Increased reproducibility over existing protocols
  • Higher sensitivity
  • Higher data confidence
Significantly Reduces Sample Preparation Time

Typically it takes less than 60 minutes (dependent on sample complexity) to achieve full digestion, whereas an in-solution digest can take up to 24 hours.

Cleaner Samples

Reduction in the number of chemicals used and the immobilized trypsin design helps mitigate against chemically induced post translational modifications (PTMs) and autolysis. This results in results which are easier to interpret.

Couple with SOLAμ SPE Plates for Desalting

When used with the SMART Digest kits for desalting, Thermo Scientific™ SOLAμ™ SPE solid phase extraction plates provide a fast, easy-to-use, robust, and easily automatable sample preparation solution for analysis of biomolecules.

Order Codes

Code Description
60109-101 Catalog Number: 60109-101
Unit Size: Each
Description: SMART Digest Trypsin Kit, with Collection plate
Format: SMART Digest Resin Pre-filled into PCR Tubes
Includes: SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate
60109-103 Catalog Number: 60109-103
Unit Size: Each
Description: SMART Digest Trypsin Kit, with SOLAμ/collection plate
Format: SMART Digest Resin Pre-filled into PCR Tubes
Includes: SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, SOLAμ SPE Plate
60109-102 Catalog Number: 60109-102
Unit Size: Each
Description: SMART Digest Trypsin Kit, with Filter/Collection plate
Format: SMART Digest Resin Pre-filled into PCR Tubes
Includes: SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, Filter Plate
60109-101-B Catalog Number: 60109-101-B
Unit Size: Each
Description: SMART Digest Trypsin Kit, Bulk Resin option
Format: SMART Digest Resin, Bulk Non-magnetic
Includes: Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer
60109-101-MB Catalog Number: 60109-101-MB
Unit Size: Each
Description: SMART Digest Trypsin Kit, Magnetic Bulk Resin option
Format: SMART Digest Resin, Bulk Magnetic
Includes: Bulk Magnetic SMART Digest Resin, SMART Digest Buffer
60109-102-B Catalog Number: 60109-102-B
Unit Size: Each
Description: SMART Digest Trypsin Kit, Bulk Resin option with Filter/Collection plate
Format: SMART Digest Resin, Bulk Non-magnetic
Includes: Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
60109-102-MB Catalog Number: 60109-102-MB
Unit Size: Each
Description: SMART Digest Trypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate
Format: SMART Digest Resin, Bulk Magnetic
Includes: Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
60109-103-B Catalog Number: 60109-103-B
Unit Size: Each
Description: SMART Digest Trypsin Kit, Bulk Resin option with SOLAμ/collection plate
Format: SMART Digest Resin, Bulk Non-magnetic
Includes: Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAμ SPE Plate
60113-101 Catalog Number: 60113-101
Unit Size: Each
Description: SMART Digest Trypsin Kit, Soluble
Format: SMART Digest Soluble Trypsin
Includes: SMART Digest Soluble Trypsin, SMART Digest Buffer, Collection Plate
60109-103-MB Catalog Number: 60109-103-MB
Unit Size: Each
Description: SMART Digest Trypsin Kit Magnetic Bulk Resin option with SOLAμ/collection plate
Format: SMART Digest Resin, Bulk Magnetic
Includes: Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAμ SPE Plate
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