Luminescence Enhancer For Solution Assays, Sapphire-II™ Enhancer (Invitrogen™)

The Sapphire-II chemiluminescence enhancer significantly reduces aqueous quenching and tune the wavelength of light emission.

• Aqueous environments reduce chemiluminescent signal intensity of 1,2-dioxetane substrates by water-induced quenching; chemiluminescence enhancers increase the emission efficiency of light production by partitioning the water from the site of chemiluminescent signal production.
• Chemically optimized formulations enhance signal intensity in solution-based applications with dioxetane-based substrate solutions (CSPD, CDP-Star, Galacton, Galacton-Plus, Galacton-Star, or NA-Star substrates).
• Choice of Sapphire-II enhancer facilitates assay development by allowing users to optimize assay signal intensity and wavelength of light emission.

Optimize Chemiluminescence Signals
Sapphire-II chemiluminescence enhancer, are essential components of tube or microplate-based assays, significantly reducing the effect of aqueous quenching. Enhancers also tune the wavelength of light emission. Sapphire-II enhancer shifts the light emission maximum to 461 nm. Sapphire-II enhancer is the optimum choice for applications requiring maximum signal intensity or blue-shifted light emission.