CaptureSelect™ Biotin Anti-Prothrombin Conjugate (Thermo Scientific™)

CaptureSelect™ Biotin Anti-Prothrombin Conjugate consists of a 13 kDa recombinant single domain antibody fragment (V_HH affinity ligand) that specifically binds with high affinity and selectivity to human prothrombin (coagulation factor II). The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces. This conjugate allows you to detect, quantitate, and characterize native and recombinant human prothrombin.

Applications for CaptureSelect Biotin Anti-Prothrombin Conjugate include ELISA, immunoprecipitation with streptavidin-coupled Dynabeads™, MSIA Streptavidin D.A.R.T.’S, Gyrolab™-based immunoassays, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).

Animal origin statement
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (V_HH) created by a proprietary technology. The V_HH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).