Pierce™ Microdialysis Plates (Thermo Scientific™)

Pierce 48-well and 96-well, 2K, 3.5K, 10K, and 20K MWCO microdialysis plates are an automation-compatible microplate with devices for the rapid dialysis of 1 to 96 samples with volumes of 10 to 1000 μL. Using the Pierce Microdialysis Plate, sample dialysis can be efficiently performed in a standard 96 deep-well plate with a minimal amount of buffer while still providing >95% removal of small molecules. The plate is compatible with standard 96-well laboratory equipment and automated liquid-handling systems, making it an ideal option for high-throughput applications.

Key Features

Each sample processed with the Pierce Microdialysis Plate is dialyzed inside a single, removable dialysis device consisting of two regenerated cellulose membranes ∼2 mm apart. The short diffusion distance and large surface area facilitate rapid dialysis, with the removal of salts and small molecules often complete in 2–4 hours. Sample is recovered using standard laboratory micropipettes. The plate seals are made of high-quality polypropylene and help protect the samples from contamination and evaporation, especially during long-term storage.

Features of Pierce Microdialysis Plate:
High yield—greater than 90% protein recovery
Rapid—dialysis completed in 2–4 hours
Easy to use—sample loading and retrieval can be done with a standard pipette tip
Flexible—detachable 8-device strips, scalable from 1 to 96 samples
Automation-compatible—plate format conforms to the SBS Microplate Standard

Each 48-well and 96-well Pierce Microdialysis Plate comes pre-loaded with twelve 8-dialysis device strips. Each dialysis device strip can be removed from the plate and separated into individual microdialysis devices, allowing only the number of needed devices to be used and eliminating waste. The sample chamber inside each microdialysis device is formed by two low-binding regenerated cellulose membranes that are rated to retain proteins and other macromolecules >2,000 Daltons while allowing removal of buffer salts and contaminants

Applications:
• Protein and DNA desalting/buffer exchange
• Removal of dyes after protein labeling
• Enzyme activity/binding assays
• Drug binding studies (also see Rapid Equilbrium Dialysis 'RED' devices)

Order Codes

Code Description
88262 Catalog Number: 88262
Unit Size: 1 plate
Description: 96-well Microdialysis Plate, 3.5K MWCO
88260 Catalog Number: 88260
Unit Size: 1 plate
Description: 96-well Microdialysis Plate, 10K MWCO
88261 Catalog Number: 88261
Unit Size: 1 plate
Description: 96-well Deep-well Plate, 2.2 mL, for Pierce 96-well Microdialysis
A50462 Catalog Number: A50462
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.1 mL, 2K MWCO
A50465 Catalog Number: A50465
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.3 mL, 2K MWCO
A50466 Catalog Number: A50466
Unit Size: 1 plate
Description: Microdialysis Plate, 48-well, 1 mL, 2K MWCO
A50467 Catalog Number: A50467
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.3 mL, 3.5K MWCO
A50468 Catalog Number: A50468
Unit Size: 1 plate
Description: Microdialysis Plate, 48-well, 1 mL, 3.5K MWCO
A50469 Catalog Number: A50469
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.3 mL, 10K MWCO
A50470 Catalog Number: A50470
Unit Size: 1 plate
Description: Microdialysis Plate, 48-well, 1 mL, 10K MWCO
A50471 Catalog Number: A50471
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.1 mL, 20K MWCO
A50472 Catalog Number: A50472
Unit Size: 1 plate
Description: Microdialysis Plate, 96-well, 0.3 mL, 20K MWCO
A50473 Catalog Number: A50473
Unit Size: 1 plate
Description: Microdialysis Plate, 48-well, 1 mL, 20K MWCO
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